Mental Health and Cacao

Mental health disorders are New Zealand’s third leading cause of health loss with conditions such as anxiety, depression, post-traumatic stress disorder (PTSD), and attention deficit disorders (ADD) affecting a large portion of people1-4. One in six people or 16.6% of the population (650,000 adults) will experience a common mental disorder at some time in their lives that will drastically impact on the health and well-being4. Socio-economically deprived New Zealanders, women, and Māori all have higher rates of mental health-related issues4. Studies have shown that the biggest barrier to people seeking help is fear of how they will be perceived within society5. Understanding mental health can help alleviate some of the fears surrounding it and also assist to better understand how we can manage it.

Anxiety

When stress becomes too much for some or just when you feel overwhelmed anxiety is a mental health disorder where people feel;

• Excessive worrying or apprehension about several of events or activities
• -Difficulty managing the worrying
• Three or more:
• Restlessness or being “on edge”
• Easily fatigued
• Irritability
• Body tension
• Sleeping problems
• Can also be associated with panic attacks and other severe symptoms

Depression

Depression can come and go, for some it can be a single episode, or othersongoing recurring episodes3. It is characterized with a depressedmood or loss in pleasure:

• Feeling down almost every day for two weeks or more
• Notably loss of enjoyment in almost all activities during this time
• Significant unintentional weight changes
• Other people notice that you are slowing down in movement or thinking
• Almost constant fatigue
• Recurrent thoughts of self-harm

Post-Traumatic Stress Disorder (PTSD)

This mental health concern is due to the unfortunate experience of a traumaticevent. Symptoms vary from person to person and may not manifest immediately.This disorder is characterised by:

• Experiencing a stressor that threatens or experiences serious injury or death
• Persistently re-experiencing traumatic event through nightmares,flashbacks, intrusive thoughts
• Avoidance of triggering emotions, memories, and reminders
• Exhibiting two types of negative alterations in cognition and mood
• May have alterations in arousal and activity
• Lasts more than one month
• Creates distress or emotional impairment
• Not due to other illnesses or medications

Attention-Deficit/Hyperactivity Disorder (ADHD)

Adults suffering from ADHD frequently experience five or more indications ofinattention and hyperactivity that impairs daily life7. Thesymptoms of ADHD include:

For those looking for natural alternatives to improve mental health many mayseek complementary or alternative medicines to treat theirsymptoms9. In Central and South American culture, the cacao beanhas always been used a sacred brain food to maintain mental balance andhappiness. Now new scientific studies are beginning to explain why cacao issuch a powerful plant to help our mental health.

How Cacao works to improve our mental health

1. With brain protecting flavonoids like epicatechin Cacao is rich in special antioxidants that protect our brain function10,11,12. It contains molecules called flavonoids, that improve memory, cognition, and learning13. Studies of people consuming flavonoids over a 10- year period showed that they preserved their cognitive performance14,15. Cacao flavonoids are rapidly absorbed in the brain and can increase cerebral blood flow reaching peak concentrations within 2-3h after eating16-19. The most prevalent flavonol found in cacao, called epicatechin20, has been independently shown to be beneficial for vascular function and blood flow21. Studies have shown that perceived fear and anxiety can negatively alter cerebral blood flow(CBF)22. So having higher levels of flavanols from cacao in your blood can help reduce anxiety, fear and improve cognition23,24. In larger clinical trials several studies showed that after 5 days or more of consuming cacao people experienced cognitive improvement in many tests, although overall behavioural changes were not noted18,25-32.

2. Through the action of methylxanthines (MXT) like theobromine The other dominant component of cacao is the family of molecules classified under methylxanthines (MTX), and their metabolic products, which act on key receptors in the brain. The MTX components in cacao include theobromine, caffeine and procyanidins11,35. Cacao only contains low levels of the stimulant caffeine11, but much higher proportions oftheobromine, that produces a similar but lesser effect in comparison36,37. So cacao can be a little stimulatory but not as much as foods with high levels of caffeine like coffee. Theobromine is the most bioavailable compound in cacao, as measured in human plasma11.It also penetrates the brain crossing the selective blood-brain barrier for direct effects14. Theobromine improves working memory, acute memory formation and memory use40. The proposed mechanism is that theobromine is an adenosine receptor antagonist, a kind of inhibitor12, but differs from the comparative molecule caffeine12. In fact, theobromine in cacao actually off sets caffeine-related anxiety and sleep disruption10. This suggests theobromine may preferentially bind to different brain regions or types of neurons to specifically enhance memory, offering many more benefits than simple caffeine.

3. By supporting our ‘bliss molecule’ - Anandamide Cacao also contains trace levels of human amines that may collectively alter mood through promoting the production of our natural bliss molecule called Anadamide. Anadamide is a human cannabinoid that regulates many stress-related functions in our nervous system. Anadamide acts to bring harmony, balance and bliss back to our natural brain function in partnership with neurotransmitters like serotonin. It is still unclear however if cacao directly or indirectly influences Anandamide. One study that has since been refuted claimed that cacao contains anandamide, which when ingested resulted in direct activation of cannabinoid receptors in the brain41. This was strongly refuted by other researchers42, however there has since been proposed a secondary hypothesis that the molecule phenylethylamine (PEA) that exists within cacao actually acts to prevent the re-uptake of cannabinoid acting molecules like Anadamide, thereby enhancing the cannabinoid receptor activation indirectly42. This follow-up response declared that the trace amounts of these amines would not be sufficient to induce a mind-altering experience. However, acute administration of cacao showed anti-anxiety responses in a rat stress-test, and long-term ingestion of cacao increased the amount of serotonin in several brain regions43.Serotonin reduces anxiety, amongst other mood-stabilising effects. The trace element PEA, found in cacao is structurally similar to serotonin and dopamine and enhances these uplifting neurotransmitters through secondary mechanisms44,45. So directly or indirectly cacao may offe rincreased levels of bliss and happiness to our brain when consumed regularly.

4. Through natural antidepressant effects Antidepressant effects of cacao have been demonstrated in laboratory studies where rats consuming it performed better in stressful situations33.In a similar human study using cacao flavonol tablets to disguise the pronounced taste, acute consumption improved cognitive function and improved self-reported mental fatigue34. Further studies investigating cacao supplementation for anxiety showed acute administration provided anti-anxiety responses, with long-term ingestion increasing the amount of serotonin in several brain regions43. These studies suggest a positive role in cacao consumption for depression and anxiety, by alleviating the symptoms experienced by those struggling.

The clinical research has provided sound evidence to support the use of cacao in the ongoing management of mental health disorders. The molecules it contains have been shown to offer brain protection, improvements in memory, enhancement in mental function as well as anti-depressant and anti-anxiety effects. These properties could be of assistance to those struggling with their mental health. The only complications with the use for such issues is alack of standardising of active ingredients. Currently there is no known standard for required levels of flavanols, methylxanthines, PEA or other important molecules and not all cacao is equal in terms of its therapeutic quality. Levels of such compounds can vary greatly depending on where and how the cacao has been grown and processed. However, daily consumption of a good quality premium cacao may offer some people benefit for the ongoing management of mental health disorders.

To learn more about cacao visit www.selenohealth.com/pages/cacao and become a cacao expert.

References

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